Journal
LANGMUIR
Volume 26, Issue 3, Pages 1520-1523Publisher
AMER CHEMICAL SOC
DOI: 10.1021/la9038792
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Funding
- ETH Zurich
- CCMX
- TRF [MRG5180240]
- EMBO
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We describe a novel platform on which to study carbohydrate-protein interactions based on ruthenium(II) glycodendrimers as optical and electrochemical probes. Using the prototypical concanavalin A (ConA)-mannose lectin-carbohydrate interaction as an example, oligosaccharide concentrations were electrochemically monitored. The displacement of the Ru(II) complex from lectin-functionalized gold surfaces was repeatedly regenerated. This new platform presents it method to monitor many different complex sugars in parallel.
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