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Recommendations for breast cancer surveillance for female survivors of childhood, adolescent, and young adult cancer given chest radiation: a report from the International Late Effects of Childhood Cancer Guideline Harmonization Group

Journal

LANCET ONCOLOGY
Volume 14, Issue 13, Pages E621-E629

Publisher

ELSEVIER SCIENCE INC
DOI: 10.1016/S1470-2045(13)70303-6

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Funding

  1. Dutch Cancer Society [UVA 2011-4938]
  2. National Institutes of Health [K05CA160724]
  3. American Lebanese Syrian Associated Charities (ALSAC)
  4. Kinderen Kankervrij (KiKa)
  5. 7th Framework Programme of the EU, PanCareSurfUp [257505]

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Female survivors of childhood, adolescent, and young adult (CAYA) cancer who were given radiation to fields that include breast tissue (ie, chest radiation) have an increased risk of breast cancer. Clinical practice guidelines are essential to ensure that these individuals receive optimum care and to reduce the detrimental consequences of cancer treatment; however, surveillance recommendations vary among the existing long-term follow-up guidelines. We applied evidence-based methods to develop international, harmonised recommendations for breast cancer surveillance among female survivors of CAYA cancer who were given chest radiation before age 30 years. The recommendations were formulated by an international, multidisciplinary panel and are graded according to the strength of the underlying evidence.

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