4.7 Article

A cell rolling cytometer reveals the correlation between mesenchymal stem cell dynamic adhesion and differentiation state

Journal

LAB ON A CHIP
Volume 14, Issue 1, Pages 161-166

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c3lc50923k

Keywords

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Funding

  1. National Institutes of Health [HL-095722, HL-097172]
  2. NSF through the Chemical and Biological Separations program [0952493]
  3. Deshpande Center for Technological Innovation at MIT
  4. Fundacao para a Ciencia e a Tecnologia, Portugal through the MIT-Portugal Program's Bioengineering Systems Focus Area [SFRH/BD/33723/2009]
  5. Pioneer Research Center Program through the National Research Foundation of Korea
  6. Ministry of Science, ICT & Future Planning [2013M3C1A3064777]
  7. National Research Foundation of Korea [2013K2A1A2053078]
  8. Directorate For Engineering
  9. Div Of Chem, Bioeng, Env, & Transp Sys [0952493] Funding Source: National Science Foundation
  10. Fundação para a Ciência e a Tecnologia [SFRH/BD/33723/2009] Funding Source: FCT

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This communication presents quantitative studies of the dynamic adhesion behavior of mesenchymal stem cells (MSCs) enabled by the combination of cell-surface receptor-ligand interactions and three-dimensional hydrodynamic control by microtopography.

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