Journal
LAB ON A CHIP
Volume 13, Issue 8, Pages 1626-1631Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3lc41171k
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Funding
- National Basic Research Program of China [2011CB808100]
- National Natural Science Foundation of China [60825406, 61108015]
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We report on the fabrication of nanofluidic channels directly buried in silicate glass with transverse widths down to less than 50 nm using three-dimensional (3D) femtosecond laser direct writing. Using this technique, integrated micro-nanofluidic systems have been produced by simultaneously writing micro- and nanofluidic channels arranged into various 3D configurations in glass substrates. The fabricated micro- and nanofluidic systems have been used to demonstrate DNA analysis, e. g. stretching of DNA molecules. Our technique offers new opportunities to develop novel 3D micro-nanofluidic systems for a variety of lab-on-a-chip applications.
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