4.7 Article

Configurable 3D-Printed millifluidic and microfluidic 'lab on a chip' reactionware devices

Journal

LAB ON A CHIP
Volume 12, Issue 18, Pages 3267-3271

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2lc40761b

Keywords

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Funding

  1. EPSRC
  2. EPSRC creativity@home scheme
  3. Royal Society/Wolfson Foundation
  4. Leverhulme Trust
  5. University of Glasgow
  6. WestCHEM
  7. EPSRC [EP/I033459/1, EP/E062814/1] Funding Source: UKRI
  8. Engineering and Physical Sciences Research Council [EP/I033459/1, EP/E062814/1] Funding Source: researchfish

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We utilise 3D design and 3D printing techniques to fabricate a number of miniaturised fluidic 'reactionware' devices for chemical syntheses in just a few hours, using inexpensive materials producing reliable and robust reactors. Both two and three inlet reactors could be assembled, as well as one-inlet devices with reactant 'silos' allowing the introduction of reactants during the fabrication process of the device. To demonstrate the utility and versatility of these devices organic (reductive amination and alkylation reactions), inorganic (large polyoxometalate synthesis) and materials (gold nanoparticle synthesis) processes were efficiently carried out in the printed devices.

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