Journal
LAB ON A CHIP
Volume 12, Issue 5, Pages 876-881Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2lc20926h
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Funding
- National Science Fund for Distinguished Young Scholars [21125522]
- National Natural Science Foundation of China [91027035, 21007015]
- Fundamental Research Funds for the Central Universities [WK1013002]
- State Key Laboratory of Chemical Engineering (ECUST) [SKL-ChE-11C01]
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A novel facile method of fabricating disposable and highly reproducible surface-enhanced Raman spectroscopy (SERS) arrays using screen printing was explored. The screen printing ink containing silver nanoparticles was prepared and printed on supporting materials by a screen printing process to fabricate SERS arrays (6 x 10 printed spots) in large batches. The fabrication conditions, SERS performance and application of these arrays were systematically investigated, and a detection limit of 1.6 x 10(-13) M for rhodamine 6G could be achieved. Moreover, the screen printed SERS arrays exhibited high reproducibility and stability, the spot-to-spot SERS signals showed that the intensity variation was less than 10% and SERS performance could be maintained over 12 weeks. Portable high-throughput analysis of biological samples was accomplished using these disposable screen printed SERS arrays.
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