Journal
LAB ON A CHIP
Volume 11, Issue 2, Pages 336-342Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c0lc00023j
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Funding
- NIBIB NIH HHS [R01 EB009761] Funding Source: Medline
- NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING [R01EB009761] Funding Source: NIH RePORTER
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In this paper, we present a monolithic PDMS micropump that generates peristaltic flow using a single control channel that actuates a group of different-sized microvalves. An elastomeric microvalve design with a raised seat, which improves bonding reliability, is incorporated into the micropump. Pump performance is evaluated based on several design parameters-size, number, and connection of successive microvalves along with control channel pressure at various operating frequencies. Flow rates ranging 0-5.87 mu L min(-1) were observed. The micropump design demonstrated here represents a substantial reduction in the number of/real estate taken up by the control lines that are required to run a peristaltic pump, hence it should become a widespread tool for parallel fluid processing in high-throughput microfluidics.
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