4.7 Article

A unified platform for optoelectrowetting and optoelectronic tweezers

Journal

LAB ON A CHIP
Volume 11, Issue 7, Pages 1292-1297

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c0lc00568a

Keywords

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Funding

  1. Center for Cell Control, a National Institutes of Health Nanomedicine Development Center [PN2 EY018228]
  2. NATIONAL EYE INSTITUTE [PN2EY018228] Funding Source: NIH RePORTER

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A platform capable of seamlessly unifying both optoelectrowetting and optoelectronic tweezers is presented. This enables the user to manipulate aqueous droplets (with electrowetting) as well as individual particles within those droplets (with dielectrophoresis). The device requires no photolithography and droplet/particle manipulation can occur continuously over the entire surface of the device. Droplet and 10 mu m polystyrene particle speeds of up to 8 mm s(-1) and 60 mu m s(-1), respectively, are demonstrated. Particle concentration within, and subsequent splitting of, a droplet is performed resulting in average concentration efficiencies of 93%. Serial concentration is also demonstrated resulting in exponentially increasing particle concentrations and a 10 x concentration increase. Finally, the platform is used to select a single cell out of a cohort and subsequently encapsulate it in its own aqueous droplet.

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