Journal
LAB ON A CHIP
Volume 10, Issue 17, Pages 2279-2282Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c004991c
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Funding
- National Science Foundation
- National Institutes of Health [EB000252]
- Bill & Melinda Gates Foundation's Grand Challenges in Global Health Initiative [37884]
- NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING [R01EB000252] Funding Source: NIH RePORTER
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A method for patterning narrow lines of biomolecules onto nitrocellulose membranes using laboratory syringe pumps is described. One syringe pump is used to drive the biomolecule solution through a needle, while another modified syringe pump acts as a one-dimensional translation stage, moving the needle across the membrane much like a pen. This method consumes very small volumes of reagents, and is a viable option for laboratory-scale fabrication and prototyping of point-of-care rapid diagnostic test strips.
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