Journal
LAB ON A CHIP
Volume 9, Issue 19, Pages 2789-2795Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b906048k
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Funding
- NIH [R21-EB006308, R01CA20003]
- NSF [ECS 0554990]
- Indiana Elks administered through the Purdue University Cancer Center
- NATIONAL CANCER INSTITUTE [R01CA120003] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING [R21EB006308] Funding Source: NIH RePORTER
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We demonstrate electrically addressable localized heating in fluid at the dielectric surface of silicon-on-insulator field-effect transistors via radio-frequency Joule heating of mobile ions in the Debye layer. Measurement of fluid temperatures in close vicinity to surfaces poses a challenge due to the localized nature of the temperature profile. To address this, we developed a localized thermometry technique based on the fluorescence decay rate of covalently attached fluorophores to extract the temperature within 2 nm of any oxide surface. We demonstrate precise spatial control of voltage dependent temperature profiles on the transistor surfaces. Our results introduce a new dimension to present sensing systems by enabling dual purpose silicon transistor-heaters that serve both as field effect sensors as well as temperature controllers that could perform localized bio-chemical reactions in Lab on Chip applications.
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