Journal
LAB ON A CHIP
Volume 9, Issue 8, Pages 1033-1036Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b820985e
Keywords
-
Categories
Funding
- Office of Naval Research [N00014-08-1-0469]
- National Institutes of Health [447850-24360]
- Armed Forces Institute for Regenerative Medicine [44785259819]
- California Institute of Regenerative Medicine (CIRM)
- ARO Institute for Collaborative Biotechnologies [DAAD1903D004]
Ask authors/readers for more resources
We report the utilization of microfluidic technology to phage selection and demonstrate that accurate control of washing stringency in our microfluidic magnetic separator (MMS) directly impacts the diversity of isolated peptide sequences. Reproducible generation of magnetic and fluidic forces allows controlled washing conditions that enable rapid convergence of selected peptide sequences. These findings may provide a foundation for the development of automated microsystems for rapid in vitro directed evolution of affinity reagents.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
