Journal
LAB ON A CHIP
Volume 8, Issue 8, Pages 1394-1397Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b803243b
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Funding
- Apulia Regional Strategic Project [PS_144]
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Producing solvent-resistant microfluidic devices is a challenge for analytical chemistry and biochemistry. We demonstrate a simple and low-cost fabrication approach for the realization of solvent-resistant microchannels based on perfluoropolyether elastomers, exhibiting very low aspect ratios (0.01). The strength of the microchannels sealing is evaluated through the maximum internal pressure (1.52 MPa) prior to device failure, due to delamination at the bonded interface. This approach allows the elastic properties of silicone elastomers, suitable for high quality external connections, to be combined with the non-swelling character of perfluoropolyethers.
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