Journal
KIDNEY INTERNATIONAL
Volume 84, Issue 6, Pages 1079-1089Publisher
ELSEVIER SCIENCE INC
DOI: 10.1038/ki.2013.377
Keywords
clinical immunology; clinical nephrology; complement; glomerulonephritis; immunology and pathology
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Funding
- Medical Research Council [G1002528] Funding Source: Medline
- Wellcome Trust [098476] Funding Source: Medline
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C3 glomerulopathy is a recently introduced pathological entity whose original definition was glomerular pathology characterized by C3 accumulation with absent or scanty immunoglobulin deposition. In August 2012, an invited group of experts (comprising the authors of this document) in renal pathology, nephrology, complement biology, and complement therapeutics met to discuss C3 glomerulopathy in the first C3 Glomerulopathy Meeting. The objectives were to reach a consensus on: the definition of C3 glomerulopathy, appropriate complement investigations that should be performed in these patients, and how complement therapeutics should be explored in the condition. This meeting report represents the current consensus view of the group.
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