Journal
KIDNEY INTERNATIONAL
Volume 80, Issue 6, Pages 572-586Publisher
ELSEVIER SCIENCE INC
DOI: 10.1038/ki.2011.223
Keywords
atrial fibrillation; heart failure; myocardial infarction; peripheral arterial disease; stroke; sudden death
Categories
Funding
- Satellite Health Care
- Bristol-Myers Squibb
- Boehringer Ingleheim
- Medtronic
- Amgen
- Bayer
- Genzyme
- GSK
- Johnson Johnson
- Novartis
- Roche
- Sanofi-Aventis
- KDIGO
- Takeda
- Abbott
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Cardiovascular morbidity and mortality in patients with chronic kidney disease (CKD) is high, and the presence of CKD worsens outcomes of cardiovascular disease (CVD). CKD is associated with specific risk factors. Emerging evidence indicates that the pathology and manifestation of CVD differ in the presence of CKD. During a clinical update conference convened by the Kidney Disease: Improving Global Outcomes (KDIGO), an international group of experts defined the current state of knowledge and the implications for patient care in important topic areas, including coronary artery disease and myocardial infarction, congestive heart failure, cerebrovascular disease, atrial fibrillation, peripheral arterial disease, and sudden cardiac death. Although optimal strategies for prevention, diagnosis, and management of these complications likely should be modified in the presence of CKD, the evidence base for decision making is limited. Trials targeting CVD in patients with CKD have a large potential to improve outcomes. Kidney International (2011) 80, 572-586; doi: 10.1038/ki.2011.223; published online 13 July 2011
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