4.7 Editorial Material

Fetuin-mineral complex: a new potential biomarker for vascular calcification?

Journal

KIDNEY INTERNATIONAL
Volume 75, Issue 9, Pages 874-876

Publisher

ELSEVIER SCIENCE INC
DOI: 10.1038/ki.2009.52

Keywords

-

Ask authors/readers for more resources

Vascular calcification is prevalent in dialysis patients and is associated with a high burden of cardiovascular disease. Fetuin-A is a potent inhibitor of vascular calcification, but the precise mechanism by which it mediates vascular calcification in uremia is unclear. Matsui and colleagues demonstrate that circulating fetuin-A forms fetuin-mineral complex in the serum of uremic rats and thereby inhibits vascular calcification. This suggests that fetuin-mineral complex may reflect extraosseous calcification stress, opening new perspectives on vascular calcification in uremia.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.7
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available