Journal
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
Volume 63, Issue 12, Pages 1389-1392Publisher
GERONTOLOGICAL SOC AMER
DOI: 10.1093/gerona/63.12.1389
Keywords
Fatigue; Gait speed; Functional status; Longitudinal studies
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Funding
- Merck Research Laboratories
- Pittsburgh Claude D. Pepper Older Americans Independence Center [P30AG-024827]
- Hartford Foundation
- National Institute on Aging [K07AG023641]
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Background. Fatigue is a common complaint among older adults, but the association of fatigue with subsequent function is not well known. Methods. This 3-year longitudinal study of older primary care patients evaluates the association of fatigue, operationalized as feeling tired most of the time, with functional status at baseline and over time. Results. After adjustment for multiple potential confounders, participants who were tired at baseline had worse Short Form-36 Physical Performance Index scores, activity of daily living scores, and gait speeds. These functional deficits persisted throughout the follow-up period. Conclusions. Fatigue in older adults is associated with functional deficits that persist for years. Further research is needed to understand the causes of fatigue and to develop specific treatments for this serious symptom.
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