Journal
JOURNAL OF VIROLOGY
Volume 83, Issue 13, Pages 6429-6434Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JVI.00293-09
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Funding
- Ministry of Education, Culture, Sports, Science, and Technology of Japan
- Japanese Society for the Promotion of Science (JSPS)
- National Institute of Allergy and Infectious Diseases Public Health Service
- Grants-in-Aid for Scientific Research [21580372] Funding Source: KAKEN
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In pro- and eukaryotic cells, RuvB-like protein 2 (RBL2) resolves Holliday junction recombination intermediates. Here, we identified RBL2 as a suppressor of influenza A virus replication. Human RBL2 appears to interfere with the oligomerization of the viral nucleoprotein, a critical step in the assembly of viral replication complexes.
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