Journal
JOURNAL OF VIROLOGY
Volume 82, Issue 11, Pages 5650-5652Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JVI.00325-08
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Funding
- NIAID NIH HHS [1 UC19 AI062623-023] Funding Source: Medline
- NCPDCID CDC HHS [R21 U01CI000354-01, U01 CI000354] Funding Source: Medline
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Influenza causes significant morbidity in tropical regions; however, unlike in temperate zones, influenza in the tropics is not strongly associated with a given season. We have recently shown that influenza virus transmission in the guinea pig model is most efficient under cold, dry conditions, which are rare in the tropics. Herein, we report the lack of aerosol transmission at 30 degrees C and at all humidities tested. Conversely, transmission via the contact route was equally efficient at 30 degrees C and 20 degrees C. Our data imply that contact or short-range spread predominates in the tropics and offer an explanation for the lack of a well-defined, recurrent influenza season affecting tropical and subtropical regions of the world.
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