Journal
JOURNAL OF VIROLOGICAL METHODS
Volume 171, Issue 1, Pages 284-286Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jviromet.2010.10.003
Keywords
HRM; Influenza; Neuraminidase; RT-PCR
Funding
- Spanish Ministry responsible for Science
- Department of Health of Castilla y Leon [EMER07/050, PI081236, GR09/0021]
- Proyectos en Investigacion Sanitaria [PI081236]
- Programa de investigacion comisionada en gripe [GR09/0021]
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Diagnostic methods based upon exclusive detection of haemagglutinin do not detect sequence variation in other gene segments of the Influenza A virus. A complementary approach is described based upon high-resolution melting curve analysis of the neuraminidase gene, an approach with the potential ability to detect small changes in the neuraminidase sequence without the need for specific probes. (C) 2010 Elsevier B.V. All rights reserved.
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