Journal
JOURNAL OF VETERINARY SCIENCE
Volume 14, Issue 3, Pages 367-371Publisher
KOREAN SOC VETERINARY SCIENCE
DOI: 10.4142/jvs.2013.14.3.367
Keywords
cell transplantation; equine; mesenchymal stem cells; umbilical cord blood
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Funding
- National Research Foundation of Korea (NRF)
- Korean government (MEST) [2010-0020265]
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Tendinitis of the superficial digital flexor tendon (SDFT) is a significant cause of lameness in horses; however, recent studies have shown that stem cells could be useful in veterinary regenerative medicine. Therefore, we isolated and characterized equine umbilical cord blood mesenchymal stem cells (eUCB-MSCs) from equine umbilical cord blood obtained from thoroughbred mares during the foaling period. Horses that had tendinitis of the SDFT were treated with eUCB-MSCs to confirm the therapeutic effect. After eUCB-MSCs transplantation, the core lesion in the SPIT was found to decrease. These results suggest that transplantation using eUCB-MSCs could be another source of cell treatment.
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