4.1 Article

Prognostic Analyses on Anatomical and Morphological Classification of Feline Lymphoma

Journal

JOURNAL OF VETERINARY MEDICAL SCIENCE
Volume 76, Issue 6, Pages 807-811

Publisher

JAPAN SOC VET SCI
DOI: 10.1292/jvms.13-0260

Keywords

feline; Kiel classification; lymphomas; prognosis

Funding

  1. Ministry of Education, Culture, Sports, Science and Technology, Japan
  2. Grants-in-Aid for Scientific Research [10J40178] Funding Source: KAKEN

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The present study was carried out to analyze the prognosis of 163 cats with lymphoma classified anatomically and cytomorphologically. Anatomically, alimentary lymphoma was the most common form and showed significantly shorter survival than mediastinal and nasal lymphomas in cats. Cytomorphologically, there was no predominant subtype in feline lymphomas. Immunoblastic type (18%), centroblastic type (16%), globule leukocyte type (15%), lymphocytic type (12%), lymphoblastic type (12%), pleomorphic medium and large cell type (10%) and anaplastic large cell type (7%) were relatively common subtypes. Most of the cats with globule leukocyte lymphoma had the alimentary form. Comparing median survival time among classifications, cats with globule leukocyte lymphoma showed significantly shorter survival than those with high-grade and other low-grade lymphomas. Furthermore, cats with high-grade lymphomas showed significantly shorter survival than cats with other low-grade lymphomas. The present study indicated the clinical significance of anatomical and cytomorphological evaluation in feline lymphomas.

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