Journal
JOURNAL OF VETERINARY MEDICAL SCIENCE
Volume 72, Issue 4, Pages 465-470Publisher
JAPAN SOC VET SCI
DOI: 10.1292/jvms.09-0283
Keywords
canine; mortality; outcome; primary IMHA; prognosis
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Funding
- Ministry of Education, Culture, Sports, Science and Technology of Japan
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Clinical courses of primary immune-mediated hemolytic anemia (pIMHA) in dogs are highly variable, however, limited information is available to predict their accurate prognoses. To evaluate the prognostic significance of clinical factors and to propose a scoring system to predict prognoses, the medical records of seventy-one dogs with pIMHA were reviewed. Overall mortality rate of does with pIMHA was 39% and most of the clogs died within 3 months from diagnosis. Sex, body weight, seasonality, packed corpuscular volume (PCV), platelet count (PLT), total plasma protein (TP), blood urea nitrogen, albumin, total bilirubin, sodium ion, prothrombin time, and fibrin/fibrinogen degradation products before immunosuppressive treatment can influence on survival time in clogs with pIMHA. A prognostic scoring system using a combination of sex, seasonality. PCV, PLT and TP can he statistically significant for raising the accuracy of prognostic prediction. Using the scoring system for prognostication in does with pIMHA may enable veterinarians to predict a prognosis easily and accurately.
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