4.5 Article

Effect of moderate exercise on peritoneal neutrophils from juvenile rats

Journal

APPLIED PHYSIOLOGY NUTRITION AND METABOLISM
Volume 40, Issue 9, Pages 959-962

Publisher

CANADIAN SCIENCE PUBLISHING, NRC RESEARCH PRESS
DOI: 10.1139/apnm-2015-0056

Keywords

juvenile rats; moderate exercise; exercise immunology

Funding

  1. Sao Paulo Research Foundation (FAPESP)
  2. State of Pernambuco Science and Technology Support Foundation (FACEPE)
  3. Coordination for the Improvement of Higher Level- or Education-Personnel (CAPES)

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Previous studies showed that moderate exercise in adult rats enhances neutrophil function, although no studies were performed in juvenile rats. We evaluated the effects of moderate exercise on the neutrophil function in juvenile rats. Viability and neutrophils function were evaluated. Moderate exercise did not impair the viability and mitochondrial transmembrane potential of neutrophils, whereas there was greater reactive oxygen species production (164%; p < 0.001) and phagocytic capacity (29%; p < 0.05). Our results suggest that moderate exercise in juvenile rats improves neutrophil function, similar to adults.

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