Related references
Note: Only part of the references are listed.Evolutionary Action Score of TP53 Coding Variants Is Predictive of Platinum Response in Head and Neck Cancer Patients
Abdullah A. Osman et al.
CANCER RESEARCH (2015)
Evolutionary Action Score of TP53 Identifies High-Risk Mutations Associated with Decreased Survival and Increased Distant Metastases in Head and Neck Cancer
David M. Neskey et al.
CANCER RESEARCH (2015)
Wee-1 Kinase Inhibition Overcomes Cisplatin Resistance Associated with High-Risk TP53 Mutations in Head and Neck Cancer through Mitotic Arrest Followed by Senescence
Abdullah A. Osman et al.
MOLECULAR CANCER THERAPEUTICS (2015)
A formal perturbation equation between genotype and phenotype determines the Evolutionary Action of protein-coding variations on fitness
Panagiotis Katsonis et al.
GENOME RESEARCH (2014)
Subcellular optogenetic inhibition of G proteins generates signaling gradients and cell migration
Patrick R. O'Neill et al.
MOLECULAR BIOLOGY OF THE CELL (2014)
Single nucleotide variations: Biological impact and theoretical interpretation
Panagiotis Katsonis et al.
PROTEIN SCIENCE (2014)
Crystal structure of a common GPCR-binding interface for G protein and arrestin
Michal Szczepek et al.
NATURE COMMUNICATIONS (2014)
Discovery and Characterization of a G Protein-Biased Agonist That Inhibits β-Arrestin Recruitment to the D2 Dopamine Receptor
R. Benjamin Free et al.
MOLECULAR PHARMACOLOGY (2014)
Accounting for epistatic interactions improves the functional analysis of protein structures
Angela D. Wilkins et al.
BIOINFORMATICS (2013)
Using Optogenetics to Interrogate the Dynamic Control of Signal Transmission by the Ras/Erk Module
Jared E. Toettcher et al.
CELL (2013)
Molecular signatures of G-protein-coupled receptors
A. J. Venkatakrishnan et al.
NATURE (2013)
GENSAT BAG Cre-Recombinase Driver Lines to Study the Functional Organization of Cerebral Cortical and Basal Ganglia Circuits
Charles R. Gerfen et al.
NEURON (2013)
Dual Control of Dopamine Synthesis and Release by Presynaptic and Postsynaptic Dopamine D2 Receptors
Andrea Anzalone et al.
JOURNAL OF NEUROSCIENCE (2012)
A new era of GPCR structural and chemical biology
Sebastien Granier et al.
NATURE CHEMICAL BIOLOGY (2012)
Dopaminergic Modulation of Synaptic Transmission in Cortex and Striatum
Nicolas X. Tritsch et al.
NEURON (2012)
Deletion of GSK3β in D2R-expressing neurons reveals distinct roles for β-arrestin signaling in antipsychotic and lithium action
Nikhil M. Urs et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Signaling Pathways Leading to Phosphorylation of Akt and GSK-3 beta by Activation of Cloned Human and Rat Cerebral D-2 and D-3 Receptors
Clotilde Mannoury la Cour et al.
MOLECULAR PHARMACOLOGY (2011)
Functional Interaction between Trace Amine-Associated Receptor 1 and Dopamine D2 Receptor
Stefano Espinoza et al.
MOLECULAR PHARMACOLOGY (2011)
Crystal structure of the β2 adrenergic receptor-Gs protein complex
Soren G. F. Rasmussen et al.
NATURE (2011)
Distinct Phosphorylation Sites on the β2-Adrenergic Receptor Establish a Barcode That Encodes Differential Functions of β-Arrestin
Kelly N. Nobles et al.
SCIENCE SIGNALING (2011)
β-arrestin-mediated receptor trafficking and signal transduction
Sudha K. Shenoy et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2011)
Third Generation Antipsychotic Drugs: Partial Agonism or Receptor Functional Selectivity?
Richard B. Mailman et al.
CURRENT PHARMACEUTICAL DESIGN (2010)
Agonist-Induced Endocytosis and Receptor Phosphorylation Mediate Resensitization of Dopamine D2 Receptors
Dongim Cho et al.
MOLECULAR ENDOCRINOLOGY (2010)
Targeted optogenetic stimulation and recording of neurons in vivo using cell-type-specific expression of Channelrhodopsin-2
Jessica A. Cardin et al.
NATURE PROTOCOLS (2010)
Evolution-guided discovery and recoding of allosteric pathway specificity determinants in psychoactive bioamine receptors
Gustavo J. Rodriguez et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Structure of the Human Dopamine D3 Receptor in Complex with a D2/D3 Selective Antagonist
Ellen Y. T. Chien et al.
SCIENCE (2010)
G Protein-coupled Receptor Kinase-mediated Phosphorylation Regulates Post-endocytic Trafficking of the D2 Dopamine Receptor
Yoon Namkung et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
G Protein-coupled Receptor Kinase-2 Constitutively Regulates D2 Dopamine Receptor Expression and Signaling Independently of Receptor Phosphorylation
Yoon Namkung et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Phasic Firing in Dopaminergic Neurons Is Sufficient for Behavioral Conditioning
Hsing-Chen Tsai et al.
SCIENCE (2009)
A Dopamine D-2 Receptor Mutant Capable of G Protein-Mediated Signaling but Deficient in Arrestin Binding
Hongxiang Lan et al.
MOLECULAR PHARMACOLOGY (2009)
Crystal structure of opsin in its G-protein-interacting conformation
Patrick Scheerer et al.
NATURE (2008)
Antagonism of dopamine D2 receptor/β-arrestin 2 interaction is a common property of clinically effective antipsychotics
Bernard Masri et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Role of β-arrestin-mediated desensitization and signaling in the control of angiotensin AT1a receptor-stimulated transcription
Mi-Hye Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand
Blaine N. Armbruster et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Functional selectivity and classical concepts of quantitative pharmacology
Jonathan D. Urban et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2007)
Comprehensive repertoire and phylogenetic analysis of the G protein-coupled receptors in human and mouse
Thora K. Bjarnadottir et al.
GENOMICS (2006)
β-arrestin-dependent, G protein-independent ERK1/2 activation by the β2 adrenergic receptor
SK Shenoy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Millisecond-timescale, genetically targeted optical control of neural activity
ES Boyden et al.
NATURE NEUROSCIENCE (2005)
An Akt/β-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior
JM Beaulieu et al.
CELL (2005)
Independent β-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2
HJ Wei et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
The stability of the G protein-coupled receptor-β-arrestin interaction determines the mechanism and functional consequence of ERK activation
A Tohgo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Apparent loss-of-function mutant GPCRs revealed as constitutively desensitized receptors
AM Wilbanks et al.
BIOCHEMISTRY (2002)