Journal
JOURNAL OF TROPICAL PEDIATRICS
Volume 59, Issue 3, Pages 203-208Publisher
OXFORD UNIV PRESS
DOI: 10.1093/tropej/fmt004
Keywords
nutrition; pediatrics; respiratory; infections
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Funding
- Fogarty AIDS International Training and Research Program of the National Institutes of Health/Fogarty International Center [5D43 TW000004]
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We prospectively determined the association between undernutrition and incidence of acute respiratory infections (ARIs) among 711 children born to HIV-infected women. Overall, underweight was associated with a 58% increased risk of ARI. Similarly, wasting (54%), very low birth weight (88%) and child HIV infection (62%) were significantly associated with increased risk of ARI during the first 2 years. Breastfeeding was associated with 52% reduction in risk of ARI only during the first 12 months of life. Among HIV-exposed, but uninfected, children, underweight, wasting and stunting were associated with 73%, 61% and 33% increased risk of ARI, respectively. Very low birthweight and advanced maternal disease stage were also associated with increased risk of ARI. Similar results were observed among HIV-infected children, except for stunting and very low birth weight. Prevention of child undernutrition could have major impact in reducing child ARI morbidity in settings of high HIV prevalence.
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