Related references
Note: Only part of the references are listed.Sensitization of metformin-cytotoxicity by dichloroacetate via reprogramming glucose metabolism in cancer cells
Yong Won Choi et al.
CANCER LETTERS (2014)
Phase 1 trial of dichloroacetate (DCA) in adults with recurrent malignant brain tumors
E. M. Dunbar et al.
INVESTIGATIONAL NEW DRUGS (2014)
PGC1α Expression Defines a Subset of Human Melanoma Tumors with Increased Mitochondrial Capacity and Resistance to Oxidative Stress
Francisca Vazquez et al.
CANCER CELL (2013)
Oncogenic BRAF Regulates Oxidative Metabolism via PGC1α and MITF
Rizwan Haq et al.
CANCER CELL (2013)
Mutual Exclusivity Analysis of Genetic and Epigenetic Drivers in Melanoma Identifies a Link Between p14ARF and RARβ Signaling
Christina Dahl et al.
MOLECULAR CANCER RESEARCH (2013)
A key role for mitochondrial gatekeeper pyruvate dehydrogenase in oncogene-induced senescence
Joanna Kaplon et al.
NATURE (2013)
Phenformin enhances the therapeutic benefit of BRAFV600E inhibition in melanoma
Ping Yuan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Expression parameters of the metabolic pathway genes pyruvate dehydrogenase kinase-1 (PDK-1) and DJ-1/PARK7 in renal cell carcinoma (RCC)
Daniel Baumunk et al.
WORLD JOURNAL OF UROLOGY (2013)
Mitochondrial oxidative stress is the achille's heel of melanoma cells resistant to Braf-mutant inhibitor
Paola Corazao-Rozas et al.
ONCOTARGET (2013)
Dysfunctional oxidative phosphorylation makes malignant melanoma cells addicted to glycolysis driven by the V600EBRAF oncogene
Arnaldur Hall et al.
ONCOTARGET (2013)
Inactivation of the HIF-1α/PDK3 Signaling Axis Drives Melanoma toward Mitochondrial Oxidative Metabolism and Potentiates the Therapeutic Activity of Pro-Oxidants
Jerome Kluza et al.
CANCER RESEARCH (2012)
Mitochondrial Respiration - An Important Therapeutic Target in Melanoma
Michelle Barbi de Moura et al.
PLOS ONE (2012)
Melanoma whole-exome sequencing identifies V600EB-RAF amplification-mediated acquired B-RAF inhibitor resistance
Hubing Shi et al.
NATURE COMMUNICATIONS (2012)
Assessing mitochondrial dysfunction in cells
Martin D. Brand et al.
BIOCHEMICAL JOURNAL (2011)
Synergistic Antitumor Effect of Dichloroacetate in Combination with 5-Fluorouracil in Colorectal Cancer
Jingtao Tong et al.
JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY (2011)
Combination therapy with vemurafenib (PLX4032/RG7204) and metformin in melanoma cell lines with distinct driver mutations
Franziska Niehr et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2011)
Dichloroacetate induces apoptosis and cell-cycle arrest in colorectal cancer cells
B. M. Madhok et al.
BRITISH JOURNAL OF CANCER (2010)
Sodium dichloroacetate selectively targets cells with defects in the mitochondrial ETC
Luke H. Stockwin et al.
INTERNATIONAL JOURNAL OF CANCER (2010)
Differential sensitivity of melanoma cell lines with BRAFV600E mutation to the specific Raf inhibitor PLX4032
Jonas N. Sondergaard et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2010)
Melanomas acquire resistance toB-RAF(V600E) inhibition by RTK or N-RAS upregulation
Ramin Nazarian et al.
NATURE (2010)
Metabolic Modulation of Glioblastoma with Dichloroacetate
E. D. Michelakis et al.
SCIENCE TRANSLATIONAL MEDICINE (2010)
The European searchable tumour line database
James Robinson et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2009)
Oncogenic B-RAF Negatively Regulates the Tumor Suppressor LKB1 to Promote Melanoma Cell Proliferation
Bin Zheng et al.
MOLECULAR CELL (2009)
Uncoupling of the LKB1-AMPKα Energy Sensor Pathway by Growth Factors and Oncogenic BRAFV600E
Rosaura Esteve-Puig et al.
PLOS ONE (2009)
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
Matthew G. Vander Heiden et al.
SCIENCE (2009)
Dichloroacetate (DCA) as a potential metabolic-targeting therapy for cancer
E. D. Michelakis et al.
BRITISH JOURNAL OF CANCER (2008)
Dichloroacetate induces apoptosis in endometrial cancer cells
Jason Y. Y. Wong et al.
GYNECOLOGIC ONCOLOGY (2008)
Dichloroacetate (DCA) sensitizes both wild-type and over expressing Bcl-2 prostate cancer cells in vitro to radiation
Wengang Cao et al.
PROSTATE (2008)
Systemic treatment with the antidiabetic drug metformin selectively impairs p53-deficient tumor cell growth
Monica Buzzai et al.
CANCER RESEARCH (2007)
A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth
Sebastien Bonnet et al.
CANCER CELL (2007)
Multiparameter metabolic analysis reveals a close link between attenuated mitochondrial bioenergetic function and enhanced glycolysis dependency in human tumor cells
Min Wu et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2007)
Controlled clinical trial of dichloroacetate for treatment of congenital lactic acidosis in children
PW Stacpoole et al.
PEDIATRICS (2006)
Why do cancers have high aerobic glycolysis?
RA Gatenby et al.
NATURE REVIEWS CANCER (2004)
Mutations of the BRAF gene in human cancer
H Davies et al.
NATURE (2002)
Share Paper
