Journal
JOURNAL OF TOXICOLOGICAL SCIENCES
Volume 38, Issue 1, Pages 151-153Publisher
JAPANESE SOC TOXICOLOGICAL SCIENCES
DOI: 10.2131/jts.38.151
Keywords
Cadmium; Microarray; Neonatal brain; Transferrin receptor (Tfrc)
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Funding
- Ministry of Health, Labor and Welfare, Japan
- Grants-in-Aid for Scientific Research [25293031, 25281026] Funding Source: KAKEN
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DNA microarray containing 30,000 genes was used to monitor the transcriptional response of the neonatal brain after cadmium (Cd) exposure. C57BL/6J pregnant mice were exposed to Cd (10 ppm) during gestation and lactation via drinking water. In a comparison between the Cd-exposed neonatal brain and control, three genes including transferrin receptor (Tfrc) were up-regulated and one gene was down-regulated.
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