Journal
JOURNAL OF TOXICOLOGICAL SCIENCES
Volume 35, Issue 6, Pages 945-946Publisher
JAPANESE SOC TOXICOLOGICAL SCIENCES
DOI: 10.2131/jts.35.945
Keywords
Arsenite; Resistance; Yeast; Fap7; Mig3
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To elucidate mechanisms of arsenic toxicity and biological defense mechanisms against arsenic, we searched for genes that, when overexpressed, conferred arsenite resistance on yeast. Employing a Saccharomyces cerevisiae open reading frame (ORF) library, four genes associated with arsenite resistance, PAP7, MIG3, TMA19, and YLR392c, were identified.
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