4.6 Editorial Material

The CTC-Chip An Exciting New Tool to Detect Circulating Tumor Cells in Lung Cancer Patients

Journal

JOURNAL OF THORACIC ONCOLOGY
Volume 4, Issue 3, Pages 281-283

Publisher

LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/JTO.0b013e3181989565

Keywords

Circulating tumor cells; Non-small cell lung cancer; EGFR mutation; CTC-chip

Funding

  1. NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING [P41EB002503, U01EB012493, R01EB008047] Funding Source: NIH RePORTER
  2. NIBIB NIH HHS [U01 EB012493, R01 EB008047, P41 EB002503] Funding Source: Medline

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Circulating tumor cells (CTCs) are rare cells that originate from a malignancy and circulate freely in the peripheral blood. The ability to capture and study CTCs is an emerging field with implications for early detection, diagnosis, determining prognosis and monitoring of cancer, as well as for understanding the fundamental biology of the process of metastasis, Here, we review the development and initial clinical studies with a novel microfluidic platform for isolating these cells, the CTC-chip, and discuss its potential uses in the study of lung cancer.

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