Journal
JOURNAL OF THORACIC IMAGING
Volume 29, Issue 3, Pages 147-154Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/RTI.0000000000000077
Keywords
diffuse fibrosis; scarring; edema; inflammation; parametric mapping
Funding
- National Institute for Health Research (NIHR) Oxford Biomedical Research Centre based at The Oxford University Hospitals NHS Trust
- University of Oxford
- British Heart Foundation Centre of Research Excellence, Oxford
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Cardiac magnetic resonance (CMR) imaging is a well-established noninvasive imaging modality in clinical cardiology. Its unsurpassed accuracy in defining cardiac morphology and function and its ability to provide tissue characterization make it well suited for the study of patients with cardiac diseases. Late gadolinium enhancement was a major advancement in the development of tissue characterization techniques, allowing the unique ability of CMR to differentiate ischemic heart disease from nonischemic cardiomyopathies. Using T2-weighted techniques, areas of edema and inflammation can be identified in the myocardium. A new generation of myocardial mapping techniques are emerging, enabling direct quantitative assessment of myocardial tissue properties in absolute terms. This review will summarize recent developments involving T1-mapping and T2-mapping techniques and focus on the clinical applications and future potential of these evolving CMR methodologies.
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