SPECTRAL, THERMAL AND BIOLOGICAL ACTIVITY STUDIES ON RUTHENIUM(II) COMPLEXES WITH SOME PYRIDYLAMINES

Complexes resulted from the interaction of [Ph3P](3)RuCl2 with 2-aminoethylpyridine (aepy), 2-hydrazinopyridine (hzpy) and dipicolylamine (dpa) with KPF6 have been isolated from ethanol. The structures of the complexes were investigated using elemental analyses, IR, magnetic moment, UV-Vis and H-1 NMR spectroscopy. The complexes have been isolated as [Ru(hzpy)(3)](PF6)(2), [Ru(hzpy)(2)(aepy)](PF6)(2), [Ru(hzpy)(aepy)(2)](PF6)(2), [Ru(dpa)(2)](PF6)(2) in an octahedral geometry. The thermal decomposition of complexes was discussed in terms of their structures and the thermodynamic parameters were evaluated. The metal complexes were screened for their antibacterial activity against bacterial species, Escherichia coli, Staphylococcus aureus, as well as fungus (Candida). The activity data show the metal complexes have potent antibacterials against one ore more bacterial species.