Journal
JOURNAL OF THEORETICAL BIOLOGY
Volume 251, Issue 1, Pages 24-34Publisher
ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1016/j.jtbi.2007.10.039
Keywords
biofilm; individual based model; bacterial fitness
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Funding
- Engineering and Physical Sciences Research Council [EP/C522702/1] Funding Source: researchfish
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Bacterial communities such as biofilms are widely recognized as being important for survival and persistence of bacteria in harsh environments. Mechanistic models of biofilm growth indicate that the way in which the surface is seeded can effect the morphology of simulated biofilms. Experimental studies indicate that genes which are important for chemotaxis also influence biofilm formation, perhaps by influencing aggregation on a surface. Understanding aggregation and microcolony formation could therefore help clarify factors influencing biofilm formation and illuminate how groups influence the fitness of bacteria. In this paper I develop an individual based model to examine how different behaviors involved in microcolony formation on a surface determine patterns of group sizes and link patterns to bacterial fitness. (c) 2007 Elsevier Ltd. All rights reserved.
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