Journal
JOURNAL OF THE SERBIAN CHEMICAL SOCIETY
Volume 75, Issue 12, Pages 1617-1623Publisher
SERBIAN CHEMICAL SOC
DOI: 10.2298/JSC091016128X
Keywords
synthesis; lignanamide; stobbe reaction; cannabisin G
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Funding
- Shandong Provincial Natural Science Foundation, China [ZR2010HM023]
- Specialized Research Foundation for the Doctoral Program of Higher Education, China [20093719120004]
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A convenient method for the synthesis of lignanamide cannabisin G, starting from vanillin, was developed. The convergent synthesis was based on the Stobbe reaction as C C bond-forming steps to give the skeleton of lignan, which was condensed with a derivative of tyramine to obtain synthetic cannabisin G for the first time.
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