Journal
JOURNAL OF THE NEUROLOGICAL SCIENCES
Volume 334, Issue 1-2, Pages 183-185Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jns.2013.08.012
Keywords
Malaria; Neuroinflammation; Post-malaria neurological syndrome; Acute disseminated encephalomyelitis; Plasmodium falciparum; Delayed cerebellar ataxia
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Post-malaria neurological syndrome (PMNS) is an uncommon, monophasic illness that occurs within two months following recovery from Plasmodium falciparum (Pf) malaria. Clinical manifestations of PMNS are variable, but published cases uniformly feature neurological and/or psychiatric symptoms without long tract signs. We describe a case of severe brainstem and spinal cord inflammation with paraplegia and sphincter involvement in a 48 year old woman following recovery from a Pf malarial illness. We propose that this case represents a previously unreported form of PMNS, which has features that distinguish it from acute disseminated encephalomyelitis, and that the recognised clinical spectrum of PMNS should be extended to include brainstem and spinal cord inflammation. (C) 2013 Elsevier B.V. All rights reserved.
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