4.4 Article

Overactivated Neddylation Pathway as a Therapeutic Target in Lung Cancer

Related references

Note: Only part of the references are listed.
Editorial Material Critical Care Medicine

Update in Lung Cancer and Mesothelioma 2012

Charles A. Powell et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2013)

Article Biochemistry & Molecular Biology

Induction of autophagy and senescence by knockdown of ROC1 E3 ubiquitin ligase to suppress the growth of liver cancer cells

D. Yang et al.

CELL DEATH AND DIFFERENTIATION (2013)

Article Pharmacology & Pharmacy

Negative Regulation of NEDD8 Conjugation Pathway by Novel Molecules and Agents for Anticancer Therapy

Tomoaki Tanaka et al.

CURRENT PHARMACEUTICAL DESIGN (2013)

Article Biochemistry & Molecular Biology

NEDDylation regulates E2F-1-dependent transcription

Sarah J. Loftus et al.

EMBO REPORTS (2012)

Article Oncology

Inhibition of the Nedd8 System Sensitizes Cells to DNA Interstrand Cross-linking Agents

Younghoon Kee et al.

MOLECULAR CANCER RESEARCH (2012)

Article Cell Biology

A Gatekeeper Residue for NEDD8-Activating Enzyme Inhibition by MLN4924

Julia I. Toth et al.

CELL REPORTS (2012)

Article Cell Biology

Roles of COP9 signalosome in cancer

Mong-Hong Lee et al.

CELL CYCLE (2011)

Article Chemistry, Organic

Stereoselective Synthesis of MLN4924, an Inhibitor of NEDD8-Activating Enzyme

Hyuk Woo Lee et al.

JOURNAL OF ORGANIC CHEMISTRY (2011)

Article Multidisciplinary Sciences

Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence

Hui-Kuan Lin et al.

NATURE (2010)

Article Multidisciplinary Sciences

An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer

Teresa A. Soucy et al.

NATURE (2009)

Article Biochemistry & Molecular Biology

Novel substrates and functions for the ubiquitin-like molecule NEDD8

Dimitris P. Xirodimas

BIOCHEMICAL SOCIETY TRANSACTIONS (2008)

Article Biochemistry & Molecular Biology

Ribosomal proteins are targets for the NEDD8 pathway

Dimitris P. Xirodimas et al.

EMBO REPORTS (2008)

Article Biochemistry & Molecular Biology

Dcn1 functions as a scaffold-type E3 ligase for cullin neddylation

Thimo Kurz et al.

MOLECULAR CELL (2008)

Article Biochemistry & Molecular Biology

Multimodal Activation of the Ubiquitin Ligase SCF by Nedd8 Conjugation

Anjanabha Saha et al.

MOLECULAR CELL (2008)

Article Biochemistry & Molecular Biology

Direct interactions between NEDD8 and ubiquitin E2 conjugating enzymes upregulate cullin-based E3 ligase activity

Eri Sakata et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2007)

Review Biotechnology & Applied Microbiology

Drug discovery in the ubiquitin-proteasome system

Grzegorz Nalepa et al.

NATURE REVIEWS DRUG DISCOVERY (2006)

Article Cell Biology

Neddylation and deneddylation regulate Cul1 and Cul3 protein accumulation

JT Wu et al.

NATURE CELL BIOLOGY (2005)

Review Cell Biology

Function and regulation of Cullin-RING ubiquitin ligases

MD Petroski et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2005)

Article Biochemistry & Molecular Biology

Mdm2-mediated NEDD8 conjugation of p53 inhibits its transcriptional activity

DP Xirodimas et al.

Article Biochemistry & Molecular Biology

Regulation of the NEDD8 conjugation system by a splicing variant, NUB1L

T Tanaka et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Biochemistry & Molecular Biology

Nedd8-modification of Cul1 is promoted by Roc1 as a Nedd8-E3 ligase and regulates its stability

M Morimoto et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)

Article Biochemistry & Molecular Biology

Targeting of NEDD8 and its conjugates for proteasomal degradation by NUB1.

T Kamitani et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)