4.2 Article

N-formylation of amine using graphene oxide as a sole recyclable metal-free carbocatalyst

Journal

JOURNAL OF THE IRANIAN CHEMICAL SOCIETY
Volume 15, Issue 12, Pages 2851-2860

Publisher

SPRINGER
DOI: 10.1007/s13738-018-1471-3

Keywords

Synthetic methodology; Graphene oxide; Hydroformylation; C-N bond formation; Recyclability

Funding

  1. National Natural Science Foundation of China [21402168]
  2. Scientific Research Foundation of Hunan Provincial Education Department [15B232]
  3. National Natural Science Foundation of Hunan Province [2018JJ2389]
  4. Hunan 2011 Collaborative Innovation Center of Chemical Engineering & Technology with Environmental Benignity and Effective Resource Utilization

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Graphene oxide (GO), an inexpensive, environment-friendly, and metal-free carbocatalyst, used for the N-formylation of amines is developed. In this reaction, GO shows good activity, selectivity, and recyclability. This strategy has an array of advantages, such as being metal free, without additive, wide-scope protocol, scalable with a low catalyst loading of 3wt%, use of readily available and recyclable carbocatalyst, and DMF as a readily available formyl source. Furthermore, this strategy provides an avenue for the convenient hydroformylation of various amines. [GRAPHICS]

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