Fast removal and determination of doxycycline in water samples and honey by Fe3O4 magnetic nanoparticles

Adsorption characteristics and doxycycline (DC) removal efficiency of Fe3O4 magnetic nanoparticles as adsorbents have been determined by investigating the effects of pH, concentration of the DC, amount of adsorbents, contact time, ionic strength and temperature. The mechanism of adsorption was also studied. The adsorption of DC to the Fe3O4 magnetic nanoparticles could be described by Langmuir-type adsorption isotherms. Short contact time between the reagents, reusability of Fe3O4 for three times after recycling of the nanoparticles, good precision and accuracy, wide working pH range and high breakthrough volume are among the highlights of this procedure. The proposed extraction and determination procedure based on magnetic nanoparticles as adsorbent was successfully applied to the determination of DC spiked in honey and various water samples. The method presented here is fast, simple, cheap and robust, and it does not require the use of organic solvents. Also, the method needs only a magnet and can be performed in any laboratory without sophisticated equipment.