Journal
JOURNAL OF THE IRANIAN CHEMICAL SOCIETY
Volume 7, Issue 2, Pages 447-454Publisher
SPRINGER
DOI: 10.1007/BF03246031
Keywords
Strecker; alpha-Amino nitriles; Zr(HSO4)(4); Solid acid
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Funding
- Isfahan University of Technology (IUT), IR Iran
- National Institute of Health [GM 033138, MH 065503, NS 033650]
- Center of Excellency in Sensor and Green Chemistry Research (IUT)
- Isfahan Science AMP
- Technology Town (ISTT)
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A mild and efficient method has been developed for the preparation of alpha-amino nitriles from the condensation of aldehydes and ketones with aniline and TMSCN in the presence of a catalytic amount of Zr(HSO4)(4) under solvent-free conditions at room temperature.
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