Journal
JOURNAL OF THE IRANIAN CHEMICAL SOCIETY
Volume 7, Issue 1, Pages 237-242Publisher
SPRINGER
DOI: 10.1007/BF03245884
Keywords
Dihydropyrimidinone; Dodecylphosphonic acid; Solvent-free; Biginelli condensation
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Funding
- Shiraz University Research Council
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Dodecylphosphonic acid is a solid Bronsted acid that catalyzes efficiently the preparation of dihydropyrimidinones by Biginelli condensation under solvent-free conditions. This protocol offers several advantages including high yields, short reaction times, easy work-up, and use of cheap, relatively moderate acidic and safe catalyst.
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