Journal
JOURNAL OF THE IRANIAN CHEMICAL SOCIETY
Volume 6, Issue 3, Pages 588-593Publisher
IRANIAN CHEMICAL SOC
DOI: 10.1007/BF03246538
Keywords
Michael addition; Indole; alpha,beta-Unsaturated electron-deficient compounds; Micellar media
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Funding
- Research Council of Yazd University
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The Michael addition of indoles to alpha,beta-unsaturated electron deficient compounds was catalyzed efficiently at room temperature in acidic micellar solution of sodium dodecyl sulfate (SDS). The substitution on the indole nucleus occurred exclusively at the 3-position in good to excellent yields, and no N-alkylation products were observed.
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