4.2 Article

The first report on the synthesis of new hantzsch N-ethyldimetyl acetal-1,4-dihydropyridines with aldehyde synthon under microwave irradiation

Journal

JOURNAL OF THE IRANIAN CHEMICAL SOCIETY
Volume 5, Issue -, Pages S91-S96

Publisher

SPRINGER
DOI: 10.1007/BF03246495

Keywords

N-ethyldimethyl acetal-1; 4-dihydropyridines 1,4-dihydripyridines; aminoacetaldehyde dimethyl acetal; ethyl acethylenecarboxylate; solvent-free; microwave irradiation

Funding

  1. Management and Programming Organization of I.R. Iran
  2. Center of Excellence in Development of Chemical Methods (CEDCM), Bu-Ali Sina University, Hamedan, Iran

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A mixture of ethyl acethylenecarboxylate, various aryl aldehydes and aminoacetaldehyde dimethyl acetal in the presence of silica gel were converted to N-ethyldimethyl acetal-1,4-dihydropyridines using microwave irradiation with good yields.

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