Journal
JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY
Volume 20, Issue 6, Pages 620-629Publisher
CAMBRIDGE UNIV PRESS
DOI: 10.1017/S1355617714000472
Keywords
Cognitive control; Cognitive flexibility; Inhibitory control; Lifespan development; Standardized testing; Validation
Categories
Funding
- Blueprint for Neuroscience Research, National Institutes of Health [HHS-N-260-2006-00007-C]
- Canadian Institute for Health Research [201963]
- NIDDK/NICHD [1699-662-6312]
- Character Lab
- NIH/NCRR [UL1RR025761]
- NIH [N01-AG-6-0007, 1U5AR057943-01, HHSN260200600007, 1U01DK082342-01, AG-260-06-01, HD05469, R01DC008552, P30AG013854]
- NINDS [U01 NS 056 975 02]
- NHLBI K23 [K23HL085766 NIA, 1RC2AG036498-01]
- NIDRR [H133B090024]
- OppNet [N01-AG-6-0007]
- Ken and Ruth Davee Foundation
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This study describes psychometric properties of the NIH Toolbox Cognition Battery (NIHTB-CB) executive function measures in an adult sample. The NIHTB-CB was designed for use in epidemiologic studies and clinical trials for ages 3 to 85. A total of 268 self-described healthy adults were recruited at four university-based sites, using stratified sampling guidelines to target demographic variability for age (20-85 years), gender, education and ethnicity. The NIHTB-CB contains two computer-based instruments assessing executive function: the Dimensional Change Card Sort (a measure of cognitive flexibility) and a flanker task (a measure of inhibitory control and selective attention). Participants completed the NIHTB-CB, corresponding gold standard convergent and discriminant measures, and sociodemographic questionnaires. A subset of participants (N = 89) was retested 7 to 21 days later. Results reveal excellent sensitivity to age-related changes during adulthood, excellent test-retest reliability, and adequate to good convergent and discriminant validity. The NIH Toolbox EF measures can be used effectively in epidemiologic and clinical studies.
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