Journal
JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY
Volume 18, Issue 6, Pages 1031-1040Publisher
CAMBRIDGE UNIV PRESS
DOI: 10.1017/S135561771200077X
Keywords
Neuropsychological test; Validation studies; Geriatric assessment; Cognition; Vascular Dementia; Alzheimer disease
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Funding
- Fundacao para a Ciencia e Tecnologia [Portuguese Foundation for Science and Technology] [SFRH/BD/38019/2007, PIC/IC/83206/2007]
- Fundação para a Ciência e a Tecnologia [SFRH/BD/38019/2007] Funding Source: FCT
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The Montreal Cognitive Assessment (MoCA) is a brief instrument developed for the screening of milder forms of cognitive impairment, having surpassed the well-known limitations of the MMSE. The aim of the present study was to validate the MoCA as well as its short version, which was proposed by the NINDS-CSN VCI Harmonization Standards for screening Vascular Dementia (VaD) patients. The results, based on a homogeneous sample of 34 VaD patients, indicate that the MoCA is a psychometrically valid and reliable instrument for cognitive screening in VaD patients, showing excellent discriminant validity. Both the full and short versions of the MoCA had excellent diagnostic accuracy in discriminating VaD patients, exhibiting an area under curve (AUC) higher than the MMSE [AUC(MoCA full version) = .950; 95% IC = .868-.988; AUC(MoCA short version) = .936; 95% IC = .849-.981; AUC(MMSE) = .860; 95% IC = .754-.932]. With a cutoff below 17 on the MoCA full version and 8 on the short version, the results for sensitivity, specificity, positive and negative predictive values, and classification accuracy were superior compared to the MMSE. In conclusion, both versions of the MoCA are valid, reliable, sensitive and accurate screening instruments for VaD patients. (JINS, 2012, 18, 1031-1040)
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