Journal
JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY
Volume 17, Issue 2, Pages 364-368Publisher
CAMBRIDGE UNIV PRESS
DOI: 10.1017/S1355617710001633
Keywords
Hypoxia-ischemia; Brain; Amnesia; Executive functions; Psychomotor; Ventricular fibrillation; Recovery of function
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Funding
- NIH [R01 HD046442]
- Office of Research and Development, Medical Research Service, Department of Veterans Affairs
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The nature of residual cognitive deficits after out of hospital cardiac arrest (OHCA) is incompletely described and has never been defined against a cardiac control (CC) group. The objective of this study is to examine neuropsychological outcomes 3 months after OHCA in patients in a. middle range of acute severity. Thirty prospective OHCA admissions, with coma > 1 day and responsive but confused at 1 week, and 30 non-OHCA coronary care admissions were administered standard tests in five cognitive domains. OHCA subjects fell into two deficit profiles. One group (N = 20) had mild memory deficits and borderline psychomotor deficits compared to the CC group; 40% had returned to work. The other group (N = 10) had severe impairments in all domains. Coma duration was associated with group. Neither group had a high prevalence of depression. For most patients within the middle range of acute severity of OHCA, cognitive and functional outcomes at 3 months were encouraging. (JINS, 2011, 17, 364-368)
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