4.7 Article

Polyglycerol coated polypropylene surfaces for protein and bacteria resistance

Journal

POLYMER CHEMISTRY
Volume 6, Issue 8, Pages 1350-1359

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4py01375a

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Funding

  1. Bundesministerium fur Bildung und Forschung (BMBF) [1315696B]
  2. Helmholtz Virtual Institute Multifunctional Biomaterials for Medicine

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Polyglycerol (PG) coated polypropylene (PP) films were synthesized in a two-step approach that involved plasma bromination and subsequently grafting hyperbranched polyglycerols with very few amino functionalities. The influence of different molecular weights and density of reactive linkers were investigated for the grafted PGs. Longer bromination times and higher amounts of linkers on the surface afforded long-term stability. The protein adsorption and bacteria attachment of the PP-PG films were studied. Their extremely low amine content proved to be beneficial for preventing bacteria attachment.

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