Journal
POLYMER CHEMISTRY
Volume 6, Issue 13, Pages 2386-2389Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4py01808g
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Funding
- Welch Foundation [AT1740]
- NSF-Career grant [DMR-0956116]
- NSF-MRI grant [CHE-1126177]
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The attachment of Histone deacetylase (HDAC) inhibitors via covalent bonds to biocompatible and biodegradable block copolymers provides a new research direction for cancer treatment. Herein, we report the synthesis and characterization of valproic acid ester pro-drug micelles of amphiphilic polycaprolactone block copolymers and their potential applications in drug delivery.
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