Electrochemical Behavior and Voltammetric Determination of Ketamine at Pulse Plating Gold Film Modified Platinum Electrode

An ultrastable chemical modified electrode (CME) was fabricated conveniently based on gold film by pulse plating of chloroauric acid on Pt disk electrode. As a novel modifying method of making CME, the CME was characterized by electrochemical impedance spectroscopy (EIS) and used as a voltammetric sensor for Ketamine. This thin gold film modified electrode exhibited excellent electrocatalysis to Ketamine oxidation. Based on this CME, detection of Ketamine by voltammetry was first erected with a fast-response and wide responding linear range. Further experiments demonstrated that this CME has good stability, repeatability and reproducibility. The established method is accurate, reliable, and can be used for the quality control of Ketamine hydrochloride injection.