4.3 Article

Silica-bonded N-Propyl Sulfamic Acid: A Recyclable Catalyst for the Synthesis of 1,8-Dioxo-decahydroacridines, 1,8-Dioxo-octahydroxanthenes and Quinoxalines

Journal

JOURNAL OF THE CHINESE CHEMICAL SOCIETY
Volume 57, Issue 5A, Pages 998-1006

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/jccs.201000139

Keywords

Silica-bonded N-propyl sulfamic acid; Acridines; Xanthenes; Dimedone; Quinoxalines; Aldehydes

Funding

  1. Research Council of Persian Gulf University, Bushehr, Iran

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Silica bonded N-propyl sulfamic acid (SBNPSA) is employed as a solid acid catalyst for the synthesis of 1,8-dioxo-decahydroacridines and 1,8-dioxo-octahydroxanthenes in high yields and short reaction times in ethanol under reflux conditions. Also, this solid acid catalyzed the reaction of 1,2-diamino compounds with 1,2-dicarbonyl compounds for the synthesis of quinoxaline derivatives at room temperature. The catalyst could be recycled and reused several times without any loss of efficiency.

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