Journal
JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY
Volume 20, Issue 6, Pages 1082-1088Publisher
SOC BRASILEIRA QUIMICA
DOI: 10.1590/S0103-50532009000600013
Keywords
Derris urucu; Leguminosae; dihydroflavonols; radical scavenging activity; antioxidant
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Funding
- Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq)
- Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES)
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Derris urucu is an Amazonian plant with insecticide and ichthyotoxic properties. Studies with this species show the presence of flavonoids, mainly rotenoids, as well as stilbenes. The ethanol extract of the leaves of Derris urucu (Leguminosae) afforded three new dihydroflavonols named urucuol A (1), B (2) and C (3), and the dihydroflavonol isotirumalin (4). Their structures were elucidated by extensive analysis of 1D and 2D NMR, UV and IR spectra and MS data and comparison with literature data. The isolated compounds (1-4) were evaluated for DPPH center dot radical scavenging activity and showed a relatively lower antioxidant ability compared to the commercial antioxidant trans-resveratrol.
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