Journal
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
Volume 23, Issue 10, Pages 1631-1634Publisher
AMER SOC NEPHROLOGY
DOI: 10.1681/ASN.2011111078
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Funding
- National Institutes of Health [RO1 DK087727, K08 DK-075846, RO1 DK-069533, RO1 DK-071837]
- Claffin Distinguished Scholar Award from the Massachusetts General Hospital
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Anemia is a common feature of CKD associated with poor outcomes. The current management of patients with anemia in CKD is controversial, with recent clinical trials demonstrating increased morbidity and mortality related to erythropoiesis stimulating agents. Here, we examine recent insights into the molecular mechanisms underlying anemia of CKD. These insights hold promise for the development of new diagnostic tests and therapies that directly target the pathophysiologic processes underlying this form of anemia.
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